Mechanisms of age-related macular degeneration. ![]() The consequences of COVID-19 pandemic on patients with monoclonal gammopathy-associated systemic capillary leak syndrome (Clarkson disease). Pineton de Chambrun M, Moyon Q, Faguer S, Urbanski G, Mathian A, Zucman N, et al. ![]() Anticancer Drug-Induced Capillary Leak Syndrome. Izzedine H, Mathian A, Amoura Z, Ng JH, Jhaveri KD. Capillary malformation–arteriovenous malformation Syndrome. Mechanism of action of histamine and target organs. Capillary action is caused by the attractive forces between the liquid molecules and the molecules of the solid surface. capillarity Gas exchange within Alveoli Alveoli are an important part of the respiratory system whose function it is to exchange oxygen and carbon dioxide molecules to and from the bloodstream histamine action and adverse effects histamine action. This property is exploited in welding, where it is used to draw the molten metal into the weld joint. Annales de Dermatologie et de Vénéréologie. Capillary action is the ability of a liquid to flow in a narrow space without the aid of external forces. Syndrome de Fegeler, angiome plan acquis ou malformation capillaire acquise : trois observations et revue de la littérature. Capillary blood sampling: national recommendations on behalf of the Croatian Society of Medical Biochemistry and Laboratory Medicine. Krleza JL, Dorotic A, Grzunov A, Maradin M Croatian Society of Medical Biochemistry and Laboratory Medicine. Archives of Disease in Childhood - Education & Practice Edition. Treasure Island (FL): StatPearls Publishing. Oxygen transport in the microcirculation and its regulation. Blood vessel adaptation with fluctuations in capillary flow distribution. The blood-brain barrier: an engineering perspective. Wong AD, Ye M, Levy AF, Rothstein JD, Bergles DE, Searson PC. Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research. Evolutionary origins of the blood vascular system and endothelium. Classification & Structure of Blood Vessels. Structure and functions of blood vessels and vascular niches in bone. Thus, capillary action could become an important choice for drug delivery systems to improve therapeutic drug efficacy, treat diseases, and improve human health.Ramasamy SK. As people pay more attention to capillary action and develop more drug delivery platforms, more unique functions and characteristics of capillary action in drug delivery will be explored. Each of the five drug delivery platforms exhibits certain unique functions that existing drug delivery technologies cannot easily achieve, hence expected to solve specific practical medical problems that are not satisfactorily resolved. To illustrate the advantages of capillary action over existing drug delivery strategies and how the capillary action could potentially address the shortcomings of the existing drug delivery strategies, we described five examples of using capillary action to design drug delivery platforms for disease treatment: marker pen for topical and transdermal drug delivery, microneedle patch with a sponge container for pulsatile drug delivery, core-shell scaffold for sustained release of growth factors, oral bolus for insulin delivery to the esophagus, and semi-hollow floating ball for intravesical and gastroprotective drug delivery. Then, we discussed the principle of capillary action in drug delivery and the influencing factors that determine its performance. ![]() This perspective begins by reviewing the principles, advantages, and limitations of the three existing drug delivery strategies: non-covalent interaction, cavity loading, and covalent conjugation. Therefore, its application in medicine and disease treatment has not been actively developed. Contrary to the fact that capillary action is ubiquitous in our daily lives, its role in drug delivery has not attracted attention.
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